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Smoking Cessation

Welcome to the smoking cessation category for physicians and pharmacists. This clinical category includes links to resources on smoking cessation guidelines, drug interactions in smokers and prescribing nicotine replacement therapy (NRT), bupropion and varenicline.

The Cochrane Collaboration
Cochrane Reviews - Tobacco

The Cochrane Collaboration is an international, non-profit, independent organisation, established to ensure that up-to-date, accurate information about the effects of healthcare interventions is readily available worldwide. It produces and disseminates systematic reviews of healthcare interventions, and promotes the search for evidence in the form of clinical trials and other studies of the effects of interventions.

Source: cochrane.org
Clinical Resource: Systematic Reviews
Register to Access Content: No

Last Checked: 13/07/15 Link Error: Report It

 

National Institute for Health and Care Excellence Guidance > Smoking cessation services

Source: nice.org.uk
Clinical Resource: Guidance
Register to Access Content: No

Last Checked: 18/05/15 Link Error: Report It

 

European Respiratory Society Guideline for Smoking Cessation in Patients With Respiratory Diseases: A High Priority, Integral Component of Therapy

Source: ers-education.org
Clinical Resource: Guideline
Register to Access Content: No

Last Checked: 17/06/13 Link Error: Report It

 

Action on Smoking and Health (ASH)

ASH provides guidance on the latest developments and evidence to help people stop smoking.

Smoking Reduction
Smoking Cessation Services
NRT or Nicotine Replacement Therapies
Varenicline or Champix
Buproprion or Zyban

Source: ash.org.uk
Clinical Resource: Various
Register to Access Content: No

Last Checked: 08/07/13 Link Error: Report It

 

Bandolier Knowledge
Smoking and stopping

Smoking is daft. Here is some of the evidence about how daft it is, and how to be smarter.

Source: bandolier.org.uk
Clinical Resource: Evidence Based Abstracts
Register to Access Content: No

Last Checked: 13/06/17 Link Error: Report It

 

Smoking Cessation

This bulletin will look at the different forms of nicotine replacement products available, their effectiveness and safety. Their use in specific patient groups will also be discussed. Bupropion, will also be reviewed.

Source: stjames.ie
Clinical Resource: Medicines Information Centre Bulletin
Register to Access Content: No

Last Checked: 08/07/13 Link Error: Report It

 

Smokefree Pharmacotherapy

This table compares the drug treatments that are available to support patients with their quit attempts

Source: saferx.co.nz
Clinical Resource: Table
Register to Access Content: No

Last Checked: 08/07/13 Link Error: Report It

 

Nicotine Replacement Therapy: Question and Answer Document

Source: webarchive.nationalarchives.gov.uk
Clinical Resource: Questions and Answers
Register to Access Content: No

Last Checked: 23/04/15 Link Error: Report It

 

Bupropion Toxicity

Bupropion (Wellbutrin®, Zyban®) is a structurally unique antidepressant (figure 1) that is also approved for the treatment of smoking cessation. Bupropion has also been used to treat attention-deficit/hyperactivity disorder (ADHD) but has not received FDA approval for this indication. It is available in immediate release, sustained release and extended release formulations.

Source: utah.edu
Clinical Resource: Poison Control Centre Newsletter
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Last Checked: 21/08/15 Link Error: Report It

 

Off-Label Drug Uses
Topiramate: Smoking Cessation

Source: thomasland.com
Clinical Resource: Journal Article
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Last Checked: 26/11/15 Link Error: Report It

 

Smoking and infertility
The Practice Committee of the American Society for Reproductive Medicine

This document reviews the evidence linking cigarette smoking with reproductive hazards for both females and males.

Source: asrm.org
Clinical Resource: Guideline
Register to Access Content: No

Last Checked: 08/07/13 Link Error: Report It

 

Smoking Cessation Pharmacotherapy: Special Populations Pearls

Smoking cessation in patients with established cardiovascular disease (CVD) has been shown to reduce the risk of recurrent heart attack and stroke. It also reduces the progression and improves symptoms of heart failure and peripheral arterial disease.

Source: usask.ca
Clinical Resource: Drug Information Services Newsletter
Register to Access Content: No

Last Checked: 19/10/15 Link Error: Report It

 

Smoking, Smoking Cessation and Breastfeeding

Source: breastfeedingnetwork.org.uk
Clinical Resource: Drug Information Factsheet
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Last Checked: 08/08/16 Link Error: Report It

 

Smoking Cessation in Psychiatric Patients

As a high prevalence (50-90%) of smoking exists in psychiatric populations compared with the general population, use of nicotine replacement therapy (NRT), particularly for persons who smoke heavily becomes important. In addition to the standard precautions recommended for NRT, consideration should be also be given to the potential for worsening of mental state in psychiatric patients and the effects on concomitant psychotropic medication.

Source: watag.org.au
Clinical Resource: Bulletin
Register to Access Content: No

Last Checked: 08/07/13 Link Error: Report It

 

Potential Drug Interactions in Smokers and Quitters

The most consistently observed effect of cigarettes on drug metabolism is an increase in the clearance of drugs that are substrates of CYP1A2. Selected drugs that interact with smoking are listed in the Table.

Source: hanstenandhorn.com
Clinical Resource: Journal Article
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Last Checked: 05/06/15 Link Error: Report It

 

Drug Interactions with Tobacco Smoke

Many interactions between tobacco smoke and medications have been identified. Note that in most cases it is the tobacco smoke—not the nicotine—that causes these drug interactions. Tobacco smoke interacts with medications through pharmacokinetic (PK) and pharmacodynamic (PD) mechanisms. PK interactions affect the absorption, distribution, metabolism, or elimination of other drugs, potentially causing an altered pharmacologic response.

Source: smokingcessationleadership.ucsf.edu
Clinical Resource: Table
Register to Access Content: No

Last Checked: 20/08/15 Link Error: Report It

 

Potential drug interactions with smoking and quitting

Chart of the most common drug interaction issues connected to the use of tobacco

Source: health.gov.bc.ca
Clinical Resource: Chart
Register to Access Content: No

Last Checked: 08/07/13 Link Error: Report It

 

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